Clinically Proven Skincare
SkinMedica Retinol Complex 1.0 is the highest concentration retinoid serum in the SkinMedica line. Formulated for experienced retinol users, it accelerates cellular renewal to visibly transform deep wrinkles, coarse texture, and uneven pigmentation.
01
Maximum-strength 1.0% micro-encapsulated pure retinol
02
Targets deep wrinkles, severe texture irregularities, and photodamage
03
Promotes collagen synthesis and cellular turnover
04
PhytoShield Complex soothes skin and minimizes flaking
How to Use
Apply one pump in the evening after cleansing.
Use after skin has adapted to Retinol Complex 0.5.
Daily SPF 30+ is mandatory.
Skin Type
Experienced retinol users and resilient skin types.
Dermatologist-Tested
Cruelty-Free
Medical-Grade Formulas
Made in the USA
Verified Customer Reviews
What Customers Are Saying
A representative sample of verified customer reviews for this product, collected from authorized SkinMedica® retailers — not reviews placed on this store. Ratings are shown across the full range, including critical reviews. Individual results may vary.
Not a retinol person
I think this is a good product overall. The dispenser works well, making it easy to control how much product comes out, and the formula applies smoothly. I switched to this retinol from another brand, hoping my skin would tolerate it better. Unfortunately, I still experience significant dryness and peeling, regardless of how much moisturizer I use. While the product itself seems effective and well-designed, I may need to switch to a gentler option that works better for my skin. Overall, it's a quality product, but it may not be the right fit for those with sensitive skin
Reviewer2 from CaliforniaVerified Purchase
Skinmedica Retinol Complex 1
Excellent product. Began to see results after about a month of use. No irritation or redness. Will buy again
Customer from Florida, Age 70-79Verified Purchase
Retinol
Great product! Yes as directed even if you don’t have sensitive skin!
LeeM from Arkansas, Age 50-59Verified Purchase
My go to every night!!!
I use this every night…If I have been in the sun I might skip a night. It is great for fine lines, seems to blur them or take them away!!!I use under my night moisturizer, I started with a lower number but now this is my go to
simsim from California, Age 60-69Verified Purchase
My Skin Loves This!
Have been using Skinmedica Retinol on my skin every other night for a year now. I have graduated to the one percent and have had no drying, redness or flaking issues. I use a night cream on top of that also. My skin is very smooth and moist. Faithful use will be my forever routine
KonaSunshine from Hawaii, Age 70-79Verified Purchase
Good retinol
Love this product! Have been using it for at least a year and a half. I stopped using it for a while and my skin did not look as good
Mare79 from Pennsylvania, Age 60-69Verified Purchase
Love the Skin Medica line!
I love Skin Medica, and I really noticed a difference in my skin brightness once I started using the products. My facialist recommended it highly, and I have been buying it ever since. I ran out of retinol, and I could see a difference when I ran out. I highly recommend this product. I know it can be costly, but as we age, this product is helping to reduce fine lines and smooth out my complexion
Customer from New Jersey, Age 60-69Verified Purchase
Strong but it works!
First time for me to try this and I use it slowly starting by once a week. It is pretty strong but I think it works and I can see the difference after using it for weeks!
Customer from California, Age 40-49Verified Purchase
Burned my face
Have been using SkinMedica .5 level retinol for several years. Tried the 1.0 & it’s burned my face badly (have mostly been in the house, wear sunscreen & a sunhat when outdoors in daylight after 9:00 am). My face is swollen, itchy, peeling & red. Threw it out and going back to the .5 level
Customer from Virginia, Age 50-59Verified Purchase
Skinmedica Retinol 1.0
Works well for me. I’m not too consistent with usage and it’s not too harsh or drying to my skin
Customer from Ohio, Age 50-59Verified Purchase
Great
This is the best retinol that I have used. It is easy to control how much you want to pump out of the bottle, absorbs quickly and works great on the skin! I will continue to use
GabrielaP from CaliforniaVerified Purchase
with two applications completely peeled my skin
I have been using retinol for many years and decided to change brands and use this product after checking a review. I used it twice an my face skin completely peeled for several days. I had to buy a CICA product to renew my skin and it took almost two weeks to stop peeling. I haven't tried the product again because I don't know if the peeling was normal or is it an allergic reaction
Lizzier from Puerto Rico, Age 60-69Verified Purchase
Strong but gentle retinol
I moved up from .5 to 1.0 retinol without flakiness or irritation
Customer from WisconsinVerified Purchase
Effective Retinol I Rotate with Other Retinoids
I like to vary my retinoids and this one does well in rotation of these. I trust this brand
nguerlain from Oregon, Age 40-49Verified Purchase
Retinol Complex
Have not used as frequently as I planned as of yet due to home emergency but still saw positive results in the short time period of use. Looking forward to starting my anticipated regular use. Have used this on the past with good results
Customer from Ohio, Age 70-79Verified Purchase
Good Product, but pricey
I liked this product, but I prefer a tretintion precription. The price is definitely better
CustomerVerified Purchase
very strong retinol
Perhaps I should have gotten a lighter dose of this retinol product. I am not new to using retinoids and I wanted to try this because it was more affordable than some others. My whole face peeled and it took a little over a week to recover. However I will say, after the peeling was over, my face looked fantastic! I recommend started with one of the lighter doses
KayKay1992 from North Dakota, Age 30-39Verified Purchase
Too Harsh
While I am a 1% retinol user for the past 8 years, I've never experienced the harshness of this product's effect on my skin. Small red spots appear and it takes several days for them to disappear. While retinol absolutely makes the skin smooth (does not affect larger wrinkles, say around the mouth), having to endure this skin damage has never been my experience with any other pharmaceutical 1% retinol. I only tried this one because the one I've used in the past is routinely out of stock. I have found that the fewer ingredients there are in a product, besides the most important one, in this case, retinol, the better. I am now mixing this product with a cheaper facial moisturizing lotion. (PM). That helps but not with the red spots. So unless you want a face that feels dry and irritated in the morning with a red spot or two when you look in the mirror, this one's not for you. I realize that my skin has gotten dryer as I age (but I get unsolicited compliments on the smoothness of it), but dropping down to 5% retinol is not in my plan. Back to my old standby!!
Reader
Rather just use prescribed Retinol
You can have a dermatologist prescribe a retinol for much less money
MelisaKVerified Purchase
Worst Skin Irritant
I have used retinol cream for about a year and decided to try this one. This is the worst, most irritating thing I have put on my face. My face became very red and felt like it was burning. My skin was extremely dry for three weeks after no matter what moisturizer I used
CustomerVerified Purchase
Probably will not buy again
I love the creamy consistency of this product but it does seem to sting my face a little, even after following with good moisturizer. I have used Replenix Retinol 10x for years and it never has given me any problems, although the consistency on that product is not as nice
CindaPVerified Purchase
Very irritating
I have been using a retinol product for a long time so I thought I could do the 1.0. But it was too irritating
AbbygrnVerified Purchase







